SkinBetter Science : AlphaRet® Overnight Cream

SkinBetter Science : AlphaRet® Overnight Cream


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SkinBetter Science products are only sold at licensed medical spas and physician clinics. In order to purchase any SkinBetter Science products, you will need to have an in-person or online consult with us.


NEW – The latest innovation in the gold standard of skin rejuvenation.

Patented formulation that uniquely brings balance back to dry, aged skin.


AlphaRet® & Intensive AlphaRet® Overnight Cream - How to Use from skinbetter science on Vimeo.


Photodamage, lines, wrinkles, uneven tone and texture.



  • Significantly reduces the appearance of wrinkles in as little as 4 weeks, with little-to-no irritation.
  • Provides moisture to help counteract the dryness associated with traditional retinoid-based products.
  • Helps to soothe and calm skin.
  • A blend of antioxidants helps neutralize free radicals.



    • PM
    • Apply a thin layer all over the face at night.
    • Not suitable for use around the eye area.
    • AlphaRet Overnight Cream contains a topical retinoid. We recommend you consult your physician before use if you are pregnant, lactating or planning to become pregnant.
    • We recommend the use of a mineral sunscreen SPF 50+ during the day.*


Sunburn Alert: This product contains alpha hydroxy acids (AHAs) that may increase your skin's sensitivity to the sun and particularly the possibility of sunburn. Use a sunscreen, wear protective clothing, and limit sun exposure while using this product and for a week afterwards.



AlphaRet - Delivers maximum retinoid efficacy with little-to-no irritation

Glycolic Acid - Helps retexturize the skin to increase efficacy of AlphaRet

Blend of unique peptides - Promotes wrinkle-smoothing and improves tone and elasticity

Bisabolol and Portulaca Extract - Help reduce the appearance of redness and calm the skin

Antioxidants (Green Tea, Co-enzyme Q10 and Vitamin E) - Provide free-radical protective benefits

Sodium PCA and Hyaluronic Acid - Provide moisturization benefits

Available in two concentrations: AlphaRest Overnight Cream and Intensive AlphaRet Overnight Cream which contains a higher level of glycolic acid for enhanced re-texturization.


Introducing One of the most Powerful

Retinoids to enter the skin

Rejuvenation market since Tretinoin

Retinoids are a critical component to skin rejuvenation. However, many people discontinue use due to erythema, dryness, flaking and other noticeable side effects. Now, from the research and development team at Skinbetter science, comes AlphaRet, a revolutionary and proprietary retinoid technology that provides visible skin rejuvenation with exceptional retinoid efficacy and tolerability. 


The Innovation:

Phase 1.

Lactic Acid replaces alcohol to create a single conjugate.
Lactic Acid (AHA as alcohol) + Retinoid = Lactyl Retinoate

Phase 2.

Ethyl Alcohol is fused with lactic acid.
Ethyl Alcohol + Lactic Acid = Ethyl Lactat

Phase 3.

The two conjugates are combined to create our new and revolutionary technology, AlphaRet. Ethyl Lactate + Lactyle Retinoate = Ethyl Lactyl Retinoate (ELR)


Optimal Effectiveness. Minimal Irritation.

When applied to skin, this double-conjugated retinoid undergoes double hydrolysis to release both the collagen-supporting retinoid and the skin retexturing lactic acid. While these two ingredients are known to be potentially irritating on their own, the natural and gradual breaking of these double bonds via hydrolysis delivers exceptional efficacy, with little-to-no irritation.