Aknicare Combi

Prevent Acne + Food Supplement

Prevent acne with the fully natural Aknicare Combi Supplement (no medicine inside).

"I find it a very useful supplement for patients with acne-prone skin to reduce acne and pimples growth, if they want to avoid Roaccutane or Isotretinoin tablets (which have more risk)."

This product is sold exclusively in clinics only.

Credit: Image taken from here

Complementing your anti-acne regimen, Aknicare Combi targets the acne causing factors from inside out. The synergistic combination of Epigallocatechin gallate and Zinc gluconate targets the pathogenesis of acne and counteracts the effect of IGF-1 (Insuline-Similar Growth Factor). Bolstered with niacin, to improve overall skin health and skin barrier function to prevent bacterial activity on the skin.

Findings have shown that excessive IGF-1, a protein hormone produced by the liver, can multiply cells that can cause hyperkeratinisation (excessive dead skin cells) and excess sebum production. These are two key acne causing factors. 

The role of IGF-1 in the pathogenesis of acne

What is it?

IGF-1 (Insulin-like Growth Factor) is a protein hormone
produced by the liver in correlation with the levels of GH (Growth Hormone).

By what is it induced?

The synthesis of IGF-1 is also promoted by the consumption of
food with a high glycemic charge (pasta, etc...), milk and derivates (Western diet).

How does it act?

IGF-1 links with its receptor (IGF-1R), expressed at the level of
keratinocytes and sebocytes, stimulating their proliferation.

This contributes to the development of Hyperkeratinization, Seborrhea, bacterial activity and inflammation.

Hence, to reduce acne (pimples), we need to counteract IGF-1 and its effects.

Functional molecules of proven efficacy. 

Epigallocatechin gallate	Zinc gluconate
Counteracts:	Counteracts:
Hyperproduction of sebum	Expression of IGF-1
Proliferation of keratinocytes	Bacterial activity
Inflammation	Inflammation

Aknicare Combi : A balanced food supplement of Epigallocatechin Gallate, Niacin and Zinc.

Aknicare Combi is based on a combination of Epigallocatechin Gallate (antioxidant, extract from green tea), vitamin B3 (niacin), and zinc (zinc gluconate), which reduces inflammation and contributes to the maintenance of normal skin and to the protection of cells from oxidative stress. 

Substances with a nutritional or physiological effect	1 tablet	% Daily recommended dose (*)
Epigallocatechin gallate	75 mg
Niacin	18 mg	112,5
Zinc	6,25 mg	62,5

(*) Daily recommended nutritional values (adults) for vitamins and mineral salts as per EU Reg. no. 1169/2011

*The product should not be used when the body mass is inferior to 30 kg.

The SDR (Slow Down Release) technology allows a prolonged release of nutritional ingredients over a period of 24 hours. 

Food supplements should not be considered as a substitute of a varied and balanced diet and a healthy lifestyle. Read carefully the warnings and the method of use mentioned on the packaging.